CRITICAL CARE

CRITICAL CARE

Critical care medicine or intensive-care medicine is a branch of medicine concerned with life support for critically ill patients.

U-TRYP

Ulinastatin is a serine protease inhibitor that reduces the pro-inflammatory response as a result of sepsis, acute pancreatitis, trauma or surgery. Ulinastatin for Injection is available as clear colourless liquid and as lyoplilized formulation.

Category - Serine protease inhibitor

Indications
1. Severe Sepsis (due to infection, trauma, burns or surgery)
2. Mild and severe acute pancreatitis.

Dosage & Administration - Please refer pack insert for further details

Presentation - 50,000 I.U. / 1,00,000 I.U.

Storage - 2- 8°C

Gamma IV

Gamma IV is a brand of Normal Human immunoglobulin 5 % for Intravenouse use . It is a sterile solution containing 4.5 %-5.5 % of human protein in 9-11 % maltose to achieve isotonicity. It contains no preservatives . Each ml contains approximately 50 mg of protein. Also present are traces of lgA and lgM. The distribution of lgG subclasses is similar to that found in normal human serum.

Category - Immunoglobulins

Indications
1. Primary Immunodeficiency (PID).
2. Kawasaki syndrome.
3. Idiopathic Thrombocytopenic Purpura (ITP).
4. Bone Marrow Transplantation.
5. Chronic B-cell Lymphocytic Leukemia.
6. Pediatric HIV-1 Infection.
7. Neonatal Sepsis.

Dosage & Administration - Please refer pack insert for further details

Presentation - 0.5 gm / 10 ml , 2.5 gm/ 50 ml , 5 gm /100 ml

Storage - 2- 8°C

THROMBOFLUX

THROMBOFLUX is a freeze-dried white powder containing Streptokinase. Strepto-kinase is a highly purified protein derived from streptococci species. Streptokinase has the property of combining with human plasminogen to form plasminogen activator. One International unit is the quantity of Streptokinase that will lyse the standard blood clot completely in 10 minutes.

Category - THROMBOLYTICS

Indications
1. Acute evolving transmural myocardial infarction.
2. Acute deep vein thrombosis.
3. Acute Pulmonary embolism.
4. Acute arterial thrombosis or embolism.
5. Occlusion of arterio-venous cannulae.

Dosage & Administration - Please refer pack insert for further details

Presentation - Vial packs of 2,50,000 I.U., 7,50,000 I.U. and 15,00,000 I.U.

Storage - 2- 8°C

AMPHOTRET

AMPHOTRET (Amphotericin B For Injection) is a freeze dried preparation of Amphotericin B for intravenous injection. AMPHOTRET is a yellow coloured cake which is to be reconstituted with Sterile Water for Injection before administration. Amphotericin B is a polyene macrolide antifungal antibiotic obtained from a strain of Streptomyces nodosus.

Category - ANTI-INFECTIVE

Indications - Visceral leishmaniasis (Kala Azar) Patients with progressive, potentially life-threatening fungal infections. Management of Invasive fungal infections

Dosage & Administration - Please refer pack insert for further details

Presentation - 50mg / vial

Storage - 2- 8°C

AMPHOMUL

AMPHOMUL (Amphotericin B Emulsion) is a sterile, yellow coloured liquid for intravenous infusion containing Amphotericin B suspended in an oil-in-water emulsion available in 50 mg/10 ml preparation. Amphomul is a proprietory product of BSV and has various formulation patents (U.S., Europe, South Africa, Japan, Australia etc.) The major goal of developing ABLE has been to attain a novel AmB preparation with lower toxicity and with at least similar efficacy compared to the parent compound, amphotericin B deoxycholate, at an economic price so that its benefits can be extended to the masses.

Category - ANTI-FUNGAL

Indications - Visceral leishmaniasis (Kala Azar) Febrile neutropenia in Cancer Patients.

Dosage & Administration - Please refer pack insert for further details

Presentation - 50 mg /10 ml

Storage - Store below 25°C

U-FRAG

U-FRAG is a freeze-dried white powder containing an enzyme Urokinase. It is isolated from fresh human urine. It activates plasminogen with the subsequent hydrolysis of fibrin and the dissolution of thrombin. Urokinase is a mixture of low (33,000) and high (54,000) molecular weight forms.

Category - Thrombolytics

Indications - Cerebral thrombosis, Cerebral infarction. Acute Peripheral vascular thrombo-embolism. Acute myocardial infarction. Acute Pulmonary embolism. Clearance of occluded catheters and shunts.

Dosage & Administration - Please refer pack insert for further details

Presentation - Vial pack of 5000 I.U. and 500000 I.U.

Storage - 2- 8°C

Amphonex

AMPHONEX (Liposomal Amphotericin B Injection I.P.) is a liposomal formulation containing Amphotericin B intercalated into the lipid bilayer. It is a lyophilized sterile product for intravenous infusion.

Category - ANTI-FUNGALS

Indications - To treat invasive fungal infection in patients who are refractory to or intolerant of conventional amphotericin B therapy.

Dosage & Administration - Please refer pack insert for further details

Presentation - 50 mg/vial

Storage - 2- 8°C

Ampholip

AMPHOLIP (Amphotericin B Lipid Complex I.P contains the antifungal agent, Amphotericin B, complexed with phospholipids. Amphotericin B is a macrocyclic, polyene, broad-spectrum antifungal antibiotic produced by streptomyces nodosus. The lipophilic moiety of Amphotericin B allows molecules of the drug to be complexed in a ribbon-like structure with the phospholipids.

Category - ANTI-FUNGALS

Indications - To treat invasive fungal infection in patients who are refractory to or intolerant of conventional amphotericin B therapy.

Dosage & Administration - Please refer pack insert for further details

Presentation - 50 mg/vial & 100mg/vial

Storage - 2- 8°C